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Neitemeier S, Jelinek A, Laino V, et al
Key drugs like semaglutide (Ozempic/Wegovy) and the dual agonist tirzepatide (Mounjaro/Zepbound) are at the forefront of a paradigm shift in treating metabolic disease
Accumulation of the precursors (UDP-GlcNAc, CDP-ribitol, and CDP-glycerol) and downregulation of the key metabolite D-Ala-D-Ala suggest the inhibition of cell wall synthesis, especially the peptidoglycan synthesis
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