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Intermediate effect sizes are considered biologically meaningful because average proportions of variance explained in physiological, ecological and evolutionary studies are usually below 7% 32
Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1Ra) and sodium-glucose cotransporter protein-2 inhibitors (SGLT2i) are currently used in T2DM management
Why This Works: The Biological Foundation The mechanism makes perfect biological sense when we understand that GLP-1 receptors are present on many types of cells, including mast cells themselves
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