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Stafeev, I., Agareva, M., Michurina, S., Tomilova, A., Shestakova, E., Zubkova, E., et al
DNA was extracted and sgRNA inserts amplified as previously described 95
10.1016/j.foodchem.2014.01.070 12
Primarily characterized by progressive degradation of articular cartilage, subchondral bone sclerosis, synovial inflammation, and weakened periarticular muscle strength (1), OA poses a substantial socioeconomic burden, with direct and indirect healthcare costs estimated at approximately 12.5% of the gross domestic product (GDP) in developed countries (2)
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