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Dose adjustments or monitoring may be required in severe kidney impairment
This is particularly relevant for patients receiving regular hydroxocobalamin injections for pernicious anaemia or malabsorption conditions
When NNMT is overactive as it tends to be in fat tissue, and increasingly with age and obesity it siphons off the very raw material your cells need to keep NAD+ topped up
Following treatment, the vitamin B12 status of herbivores should be maintained by dietary supplementation with cobalt
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