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What does this imply for the optimal profile of a winning oral obesity therapeutic
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Serious safety concerns for tirzepatide include: Boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of MTC or MEN2) Risk of pancreatitis Gallbladder disease Acute kidney injury from dehydration Hypoglycemia (when used with insulin or sulfonylureas) Serious safety concerns for orlistat include: Rare cases of severe liver injury Risk of oxalate nephropathy and kidney stones Nutritional considerations also warrant attention
Sleep, Mood, and Physical Tension Often Overlap A person may have trouble falling asleep, wake up often during the night, or sleep for hours and still feel unrested in the morning
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