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As patients are switching back to the name-brand medications, its important that we reconcile their medications and counsel them to stop usage of the compounded version
The gene responsible for type 4 Bartter syndrome encodes the common accessory -subunit of the voltage-gated Cl channels identified as ClC-Ka and ClC-Kb (the CLCNK channels)
Strong evidence should include improved recipient-cell bioenergetics, tracking of donor-specific mitochondrial DNA or proteins, ultrastructural or high-resolution live-cell confirmation, loss-of-function experiments, and functional rescue [31,32,33,34,35]
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