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If further studies do reveal these drugs to have a significant impact on some of the worlds deadliest and most debilitating diseases, it may yet transpire that semaglutide really is the wonder drug we have been waiting for

It is mainly studied for its ability to interfere with the FOXO4-p53 interaction , a pathway associated with the survival of senescent cells

The SURMOUNT clinical trials demonstrated that tirzepatide achieved up to 22.5% body weight reductionthe highest efficacy reported for any weight loss medication to date

The publication, A Novel, Widespread Impurity in Mass-Compounded Tirzepatide/B12 Products, is available here