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While anyone can benefit from healthy B12 levels, certain groups are more likely to experience deficiencies and may see greater advantages from supplementation: Vegans and vegetarians: B12 is primarily found in animal products, making supplementation critical for those on plant-based diets
These effects are well-documented with exogenous GH administration and represent the main metabolic risk of elevated growth hormone levels
Dual roles of astrocyte-derived factors in regulation of blood-brain barrier function after brain damage
Further, serious pathological consequences due to the passage of large macromolecules like giant serum proteins into the brain can cause damage to BBB
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