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This review will cover how rhizobia tolerate stresses, and how aspects of these tolerance mechanisms play a role in signal exchange between rhizobia and legumes

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In short, MTHFR initiates the conversion of folate (vitamin B9) to its functional form 5-methyltetrahydrofolate 93,94 , which on its turn acts as a coenzyme of methionine synthase for the formation of methionine from homocysteine 93,94