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Key takeaways Ozempic is a glucagon-like peptide-1 agonist approved for Type 2 diabetes mellitus, taken once a week by subcutaneous injection

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These medications work by activating receptors in the pancreas to enhance insulin release and decrease the release of another hormone, glucagon, said Brooks Cash, MD, professor and chief of gastroenterology, hepatology, and nutrition at UTHealth Houston

Weight gain associated with hypothyroidism often improves once thyroid hormone levels are adequately replaced, so it is worth confirming that your current levothyroxine dose is appropriate before pursuing additional weight management interventions