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Vitamin B12 is an essential nutrient involved in energy production, red blood cell formation, and nervous system function
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In the blood stream as nicotinic acid, it can cause skin flush and this reaction is actually responsible for the tolerable upper limit (UL) for niacin at 35 mg/d for adults in US (20)
Inform patients using these concomitant medications of the risk of hypoglycemia and educate them on the signs and symptoms of hypoglycemia
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