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moreover, it has been reported that GLP-1RA down-regulated AT1 and up-regulated AT2 in cardiomyocytes, glomerular capillaries and proximal tubules of the renal cortex in rats (73, 74, 77), resulting in a protective effect against ANG II-induced cardiac and kidney fibrosis (73, 74, 77)
Early intervention and addressing deficiencies are key to maintaining healthy bodily function
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While surgery, radiotherapy, and postoperative adjuvant chemotherapy have improved the prognosis of patients with PC, the recurrence rate remains alarmingly high [30]
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