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A study published in The New England Journal of Medicine in February 2021 focusing on the use of semaglutide (sold as Ozempic, Wegovy, and Rybelsus) for weight loss showed that people lost an average of 6.9 kg (or about 15.2 pounds) of body weight at the end of 40 weeks

Semaglutide and Mood Changes Since Semaglutide influences appetite and blood sugar, it can also affect mood

Similarly, GLP-1R activation on the axons from dispersed SPNs in the ICN, and possibly CAA, may account for other, rarer side effects of GLP-1R agonists

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