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Gastrointestinal adverse events - predominantly nausea, vomiting, diarrhea, and constipation - are the most common class effects, occurring in 20%-60% of patients depending on the agent and dose, and are typically of mild-to-moderate severity, dose-dependent, and most prominent during titration
Studies have indicated that, in human NAFLD patients, increased PARP activity could potentially lead to NAD + depletion and mitochondrial dysfunction 164
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These findings further validate the extraordinary antioxidant capacity of G/D-CuP, emphasizing its promise for use in wound repair
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