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95% CI [0.150.92])
LC also affects mitochondrial activity by boosting mitochondrial biogenesis and decreasing oxidative stress
Researchers planning new work should consult the most current literature on this compound class to position findings against the broader mechanism-niche framework
In one of the longest published studies until today (with a follow-up of 6 years) it was clearly shown that in patients with T2D and NAFLD the severity of both steatosis and fibrosis were strongly and inversely related to the Matsuda Index of insulin sensitivity, emphasizing the crucial role of PIO (currently the most well-studied TZD) that targets IR directly to its genesis [128]
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