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An effective treatment might require either utilization of multiple drugs which target the individual pathological processes which underlie the neurodegenerative disease or the use of a single agent which could influence multiple pathological processes

This results in an increasing number of clinical trials

NSL literature pointer PMID 8837953 L-Carnitine laboratory index [PMID: 8837953] National Science Labs indexing note for PMID 8837953: review the PubMed methods, models, and limitations before citing

In preclinical models, simultaneous deficiency in NAD+ and GSH is associated with accelerated mitochondrial dysfunction