glp-1 receptor meds Benefits and Risks of Agonists Outlined New GLP-1 Guidelines for Type

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doi: 10.1186/s40478-021-01180-z 229 YangYZhangJMaDZhangMHuSShaoSet al

HGH plays a crucial role in regulating body composition, promoting fat metabolism while protecting lean muscle tissue

vitamin D intake ~20% of recommendations Lean mass risk: protein + calcium insufficiency may contribute, alongside other drivers B-vitamins: thiamine and cobalamin deficits appear to increase over time Clinical takeaway (my approach): GLP-1s dont cause malnutrition in everyone but they can unmask risk in the wrong context (older adults, low-protein diets, restrictive eating patterns, prolonged nausea/vomiting, rapid weight loss, post-bariatric patients)