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The primary mechanism involves direct upregulation of vascular endothelial growth factor (VEGF) and VEGFR2 receptor expression a process documented across more than 40 individual published studies

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3 MATERIAL AND METHODS 3.1 MATERIALS 3.1.1 ANIMALS Albinic rats from the wistar race were used, from the biothery of the Psychobiology Departament in So Paulo Federal University, where they were kept to the temperature of 23 2C, with clear-dark cicle of 12 hours and free access to water and food (Pellets Labina)

Injection Frequency : For patients requiring frequent B12 injections, using a thinner gauge needle (especially for SC injections) can reduce tissue trauma and discomfort over time