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Mitochondrial DNA (mtDNA) depletion and mutations in certain mitochondrial genes are linked to reduced insulin secretion and increased oxidative stress, although studies on the exact mechanisms are scarce ( 2.4.1 Basic science research Similarly, in the context of PD, mitochondrial dysfunction can drive neurodegeneration
The FDA's 2023 Category 2 classification specifically restricts compounding pharmacies, while dietary supplements are regulated under DSHEA through a different pathway
doi: 10.1056/NEJMoa2302392
All analyses were conducted in SAS 9.4 (Cary, NC, USA)
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