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The weight loss data confirm that continued treatment beyond 48 weeks produces additional weight reduction: The 28.7% at 68 weeks exceeds the 24.2% at 48 weeks from Phase 2, representing approximately 4.5 additional percentage points of weight loss over the additional 20 weeks of treatment
The percentage of participants achieving clinically meaningful thresholds (5%, 10%, 15%, 20%+ weight loss) exceeded anything previously seen with GLP-1 based therapies
The relationship works both ways: having a mental health condition also increases the risk of developing diabetes
The committee considered ulcerative colitis
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