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In the functional coupling between LAT1 and ASCT2, glutamine enters the cancer cell through ASCT2, which then effluxes out of the cell via LAT1 coupled to the entry of leucine 115 (Fig

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Notably, there were no significant differences in locomotion and movement between the Cse / and Cse +/ groups under any condition, indicating that the weight loss is not attributable to increased physical activity in Cse / mice, and that they do not exhibit lethargy (Fig