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It is likely that the larger number of statistically significant changes to the microbiome observed in the groups switched from WD to LD reflects their more numerous exposures to different diets, longitudinal changes in dietary exposure, the stress associated with diet switch, the negative energy state achieved by treatment and/or diet-driven weight loss, or a combination of these factors, but it may also be related to differences in terminal body weight and fat mass since both adiposity and diet composition have been shown to modulate the mouse gut microbiome profile

Specifications Storage & Handling In lyophilized form, AOD-9604 research material should be stored at -20C in a sealed container, protected from moisture and direct light

Contributes to anti-ageing, longevity, and sustained energy

Mechanistic tool in preclinical work: Used to explore lipid and glucose metabolism pathways in controlled models of energy balance