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Common symptoms include: Persistent fatigue Low energy levels Shortness of breath Dizziness or feeling faint Irregular heartbeats (palpitations) Pale or yellowish skin Reduced appetite or unintentional weight loss If left untreated, B12 deficiency can lead to serious complications, including nerve damage, cognitive issues, and changes in mood
In aged mice, it improved testosterone levels, sperm quality, and spermatogenesis by enhancing the testicular microenvironment (7)
ALDH2: aldehyde dehydrogenase 2
Other studies show that Cotaduide could intervene and reverse NASH through improving metabolism in the liver including lipid and glucose metabolism via GCGR in mice, suggesting that Cotaduide may be a potential and viable therapeutic as a targeted drug intervention to reverse disease progression of NASH (131)
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