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The medication is not known to cause direct renal toxicity or to be nephrotoxic at therapeutic doses
doi: 10.1172/jci.insight.160345 15 MaloneAFWuHFronickCFultonRGautJPHumphreysBD
27 , e13211 (2022)
1,2 The dose-by-dose data from the published trials: TRIUMPH-4s 18.2% discontinuation rate at 12 mg is more than three times higher than TRANSCEND-T2D-1s 5.1% on the same dose
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