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It signals to the brain that food has arrived, slows gastric emptying so nutrients absorb more gradually, and stimulates insulin release in a glucose-dependent manner
While some insurance plans may cover B12 injections for diagnosed deficiencies, coverage for weight management purposes may often require specific medical documentation and prior authorization
For context, NICE guidance on existing approved GLP-1 receptor agonists for example, NICE TA875 (Semaglutide for managing overweight and obesity, 2023) acknowledges GI side effects as a recognised class effect and supports gradual dose escalation to improve tolerability
This is typically prescribed for patients who require additional glycemic control and weight loss
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