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Importantly, the observed oxidative damage and mitochondrial impairment following GCLC knockdown were reproduced across multiple assays and time points, reinforcing its critical role in redox regulation and cellular viability [31,32,33]

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Contrarily, generally no new vessels grew in BPC 157treated rats (i.e., those that did form in the limbus did not make contact with the penetrated area) (Masnec et al., 2015), showing that BPC 157 therapy may acknowledge also the angiogenic privilege of the corneal avascularity as essential for corneal wound healing (Tshionyi et al., 2012)

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