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There is a single report of a successful pregnancy yielding a healthy child (62), but no other information is available
The core biologic patent expires in 2028, with the 12-year biologic exclusivity running to similar or slightly later dates
De Vincenzo R, Ferlini C, Distefano M, Gaggini C, Riva A, Bombardelli E, Morazzoni P, Valenti P, Belluti F, Ranelletti FO, Mancuso S, Scambia G (2000) In vitro evaluation of newly developed chalcone analogues in human cancer cells
1 kg of the avocado seed powder was mixed with 2000 mL of distilled water and the solution was kept for a duration of 24 h
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