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In the 23andMe database, we observed rs10305420 to be associated with a number of traits (Supplementary Table 17), including T2D and traits linked to glucose metabolism
3.3.4 Pharmacodynamics After Multiple Doses of Oral Semaglutide In subjects with T2D, a statistically significant decrease in HbA 1c from a mean baseline level of 7.5% was seen after 10 weeks of treatment with 40 mg oral semaglutide versus placebo (treatment difference in change from baseline 1.5% [95% CI 1.8, 1.3]
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On the other hand, regarding the injection, there are no timing restrictions
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