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Synopsis This study investigates the impact of excessive glutathione intake on breast cancer chemotherapy resistance, showing that higher intake is linked to increased recurrence rates and poor prognosis, emphasizing the need for standardized glutathione usage during treatment
ROC curve analysis evaluated the diagnostic performance of thalamic GSH, with AUC, sensitivity, specificity, and optimal cutoff values (Youdens index) calculated
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The researchers used Annexin-V FACS analysis and DNA laddering to demonstrate that Sag activated apoptosis in the sensitive cell lines in a dose- and time-dependent manner
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