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GH stimulation may theoretically encourage tumor growth, so this therapy is avoided in anyone with an active malignancy or a history of cancer that is not in complete remission
It is important to note that whilst GLP-1 receptor agonism is well characterised in approved medicines, some mechanistic claims relating to GIP and glucagon receptor activity in humans are based on preclinical data and early clinical findings, and the relative contribution of each pathway in humans is not yet fully elucidated
Semaglutide 2.4 mg (Wegovy) produces approximately 15-17% weight loss in similar trials
MEDICAL EMERGENCY If you suspect you have SJS, call emergency services or visit an emergency care facility right away
