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Researchers consulting recent reviews should attend to both the foundational mechanism papers cited in the references and the contemporary expansion-era publications that document ongoing methodological refinements and emerging research applications

They are often prescribed to treat or prevent vitamin B12 deficiency, which can result from various conditions like pernicious anemia or gastrointestinal disorders that affect the absorption of nutrients

The basis was the findings that DSIP modulates endogenous opioid peptidergic systems and has a significant effect on circadian rhythms and cortisol levels