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Researchers have proposed several non-exclusive frameworks, including blood-brain-barrier transport of an endogenous peptide, interaction with the stress axis, circadian and pineal signalling via the alpha-1-adrenergic receptor (PMID 3029331), and neuroprotective activity
ATB 0,+ belongs to the broad spectrum of AA transporters and its presence at the luminal side could be explained as a gate-keeper, to ensure AA delivery into the brain under certain pathological conditions
Clinicians value this product for its versatility, as it can be administered either via slow intravenous injection or diluted for infusion depending on treatment requirements
Nitric oxide and cisplatin resistance: NO easy answers
