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A double-blind, randomized controlled trial using 2% topical oxidized glutathione (GSSG) demonstrated significant skin-lightening effects after 10 weeks ( Watanabe et al., Clinical, Cosmetic and Investigational Dermatology, 2014 )
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Most users take one strip daily, often before bed since growth hormone is naturally released during sleep
But, we also know that depression and suicide increase in the adolescent and young adult population regardless
However, the long-term safety of these medications, including their potential associations with cancer risk 59 and other uncommon events, warrants further investigation
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