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The primary antibodies used in the immunohistochemistry included: rabbit anti-S100 (1:1000, Abcam ab41548), mouse anti-S100 (1:500, Sigma S2532), guinea pig anti-GABA (1:200, Millipore ab175), rabbit anti-MAOB (1:200, Abcam ab175136), chicken anti-GFAP (1:1500, Abcam ab4647), rabbit anti-ABAT (1:500, Abcam ab108249), and rabbit anti-putrescine (1:200, MyBiosource MBS2090435)

D2O (25 l) containing 2 mM 3-(trimethylsilyl) propionic-2,2,3,3-d4 acid sodium salt (TSP-d4) was then transferred to a separate NMR nanotube

Its core pathophysiological characteristics are intricately intertwined with abnormal iron and lipid metabolism, oxidative stress, mitochondrial dysfunction, and neuroinflammation, driving the progressive degeneration of dopaminergic neurons in the substantia nigra (SN) ( Figure 2 )

MSM may not be marketed as an immune supplement, but its benefits directly support immune resilience and systemic health