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In clinical trials, tirzepatide demonstrated significant reductions in hemoglobin A1c levels (up to 2.5% reduction in SURPASS diabetes trials) and body weight (up to 20% reduction in SURMOUNT obesity trials) compared to placebo and other medications
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management PubMed record
doi 10.1111/apt.18138 99 WildingJPBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al
They are potent stimulators of postprandial insulin secretion under hyperglycemic conditions and contribute to approximately 70% of the physiological postprandial insulin secretion
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