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In mammalian cells, the caspase-3 is a 32 kDa inactive precursor requiring cleavage at specific aspartate residues to be converted into an active protease when cells receive the signal of apoptosis 18
Increases in glutathione returned to baseline within a month of cessation of oral therapy
This drug belongs to a class of antidepressants called serotonin-norepinephrine reuptake inhibitors (SNRIs), which are highly regarded for their effectiveness in treating neuropsychiatric disorders
Gastrointestinal side effects such as nausea and delayed gastric emptying may indirectly disrupt sleep in some patients
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