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Pan Afr Med J 31 George J, Tsutsumi M, Tsuchishima M (2019) Alteration of trace elements during pathogenesis of N-nitrosodimethylamine induced hepatic fibrosis
Plasmid construction The gene encoding acyl-CoA synthetase medium-chain family member 4 (ACSM4) from Rattus norvegicus was chemically synthesized and ligated into plasmid pRS425 (GENEWIZ, Suzhou, China)
Its primary mechanism involves activating hepatocyte growth factor (HGF) and c-Met signaling, which plays crucial roles in neuronal growth and synaptic formation
The organ damages following hyperglycemia/ROS stress can be hindered by initiating good glycemic control very early, but is not easily reversed if poorly handled over a longer time period 19
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