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I use NAC quite a bit in my patients with hypothyroidism and Hashimotos disease because it not only does the above, but it also protects the thyroid gland from damage due to inflammation
An OA mouse model was successfully established by injecting monosodium iodoacetate (MIA) in mouse knee joints 25 , specifically, involving anesthetic administration with 1.25% tribromoethanol (Bimake, M2920) at a dose of 0.2 mL/10 g body weight, followed by intra-articular injection of 10 L MIA (50 mg/ml, Sigma-Aldrich, 57858-25G-F) into the right knee joint using a 30-gauge needle
It has a clinically significant drug interaction profile, including documented interactions with certain antifungals, antibiotics, and other compounds, and requires provider monitoring during use
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