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In a Phase I study with recombinant human thymosin beta-4, the terminal half-life was about 0.5 to 2.08 hours, for example 1.02 hours at 0.5 microg/kg and up to 2.08 hours at 25 microg/kg, with linear, non-accumulating kinetics and dose-proportional Cmax Wang et al., 2021

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These studies consistently highlight GHK-Cu's broad tissue-remodeling properties in preclinical models

Maintenance dosing after weight loss may reduce to 1.8-2.0mg weekly to sustain results while minimizing cost and side effects