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doi: 10.1038/s41556-019-0287-4 69 HuangWHicksonLEirinAKirklandJLermanL
Eur.J Ophthalmol
Preclinical and human studies have shown that ER is abundantly expressed in the hypothalamus, particularly in the preoptic area (POA), ventromedial nuclei (VMN), amygdala, and periventricular nuclei (PV)
In the landmark SURMOUNT-1 trial, participants achieved average weight reductions after 72 weeks of treatment of: approximately 15% with the 5 mg dose
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