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Mounjaro can cause alternating bowel changes, including periods of constipation and diarrhoea, because it slows digestion and can change gut movement as your body adapts to it

Sima A, Calvani M, Mehra M, et al

Notably, a Medicare GLP-1 Bridge pilot begins July 1, 2026 with a $50 monthly copay for eligible enrollees a change from the old rule that Medicare never covered weight loss drugs

Dedicated long-term trials investigating the benefits of such therapies on hospitalisation, major cardiovascular adverse events and all-cause mortality are required