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& Healy, D

This suggests that some therapeutic benefits of canagliflozin could result from the activation of AMPK, rather than inhibition of SGLT2 ( DPP-4 inhibitors These compounds, by preventing deactivation by dipeptidyl peptidase-4 (DPP4) inhibitors, improve the concentration of endogenous incretins (Vangoitsenhoven et al., 2012)

But millions are now taking these drugs far beyond those boundaries

Pancreatic cancer remains a relatively rare disease, affecting approximately 10,500 people annually in the UK, with established risk factors including smoking, obesity, chronic pancreatitis, family history, age, and long-standing diabetes