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Consistent with our findings in mice, liraglutide treatment caused a 1.6 logfold increase in PCSK1 expression in the -1 subcluster compared with control (Figure 4, A and B, and Supplemental Figure 4A
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Because GLP-1 medications can improve fertility by restoring ovulation, patients trying to conceive need specific guidance: GLP-1 medications should be stopped at least two months before attempting to conceive
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