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The medical term drug-induced liver injury (DILI) refers to any liver damage caused by drugs, whether symptomatic or not

Moreover, in a double-blind crossover study, Reichard and Elder observed significant improvements of accuracy in a choice reaction time task administered to hyperkinetic children with the intake of 6.0 mg/kg body weight of caffeine 29

If it impacts the testicular microenvironment, it could enhance sperm count or motility, but data are limited and the mechanism is different than how it might act in ovaries or endometrium