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The composition of the microbiome acquired in early childhood is critical for shaping the immune function and metabolic state of infants and adults (37)

Early recognition and treatment are essential, as prolonged deficiency can lead to potentially irreversible nerve damage

Maintaining healthy collagen levels helps support the skins resilience and reduces the visible impact of environmental stressors, including sun exposure

Beyond these three papers, review articles referencing the human peptides discovery in the 1970s continue to shape how researchers frame new hypotheses, particularly around why plasma concentration declines with age and what that means for tissue-repair capacity over time