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Zinman B, Bhosekar V, Busch R et al (2019) Semaglutide once weekly as add-on to SGLT-2 inhibitor therapy in type 2 diabetes (SUSTAIN 9): a randomised, placebo-controlled trial

Importantly, current guidelines stress that AOMs should be prescribed as part of a comprehensive weight management program that includes dietary counseling, physical activity, behavioral therapy, and regular monitoring

They can also contain undisclosed and potentially hazardous ingredients

Many weight-loss experts now frame GLP-1 therapy similarly to chronic-disease management: your brain's appetite-regulation system has been shaped by years of overeating patterns, making it chronically dysregulated