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Dual Agonist: Focused and Effective Dual agonists, targeting GLP-1 and GIP receptors, are well-established in the treatment landscape
GLP-1 receptors in brain reward circuits may modulate dopamine signalling and impulse control, though mechanisms are theoretical
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Animal studies, particularly in rodents, have shown that high-dose GLP-1 exposure can lead to pancreatic ductal proliferation and, in some cases, inflammatory changes
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