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Its abnormal expression is associated with many human metabolic diseases (such as cancer, cataracts, Antley-Bixler syndrome, autoimmune disorders, metabolic liver disease and neurodegeneration) 2
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In general, essential fatty acid deficiency (i.e., deficiency of both ALA and LA) has been observed only in patients with chronic fat malabsorption, cystic fibrosis, or those on parenteral nutrition without PUFA (86, 95) (see the article on Essential Fatty Acids)
Questi effetti sono attribuiti alla sua azione sul sistema NO, che consente un aggiustamento del tono vascolare in base alle condizioni fisiologiche
