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The LEADER trial, a landmark study, has provided compelling evidence of its cardiovascular benefits [7]

Clinical obesity is characterized as a chronic illness caused by excess body fat, leading to organ dysfunction and limitations in daily activities

In 2004, researchers conducted a meta-analysis of 61 randomized controlled trials evaluating GLP-1 RAs, sodium-glucose co-transporter-2 inhibitors (SGLT2i), dipeptidyl peptidase 4 inhibitors (DPP-4i) and didnt find an increased risk of diabetic retinopathy events with GLP-1 RAs or any of the other classes of antihyperglycemic medications

When combined with nutrition and lifestyle changes, many patients experience meaningful, steady progress over time