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To investigate the impact of production methods on the stability and impurities of semaglutide drug substances and products and their potential impact on drug quality, efficacy, and safety RP-HPLC analysis was conducted using a C18 column with a mobile phase consisting of acetonitrile, isopropyl alcohol, water and 0.08 M ammonium phosphate [88]
The mean baseline body weight was 108 kg, and mean BMI was 37 kg/m2
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